There are multiple ways to manage rotations depending on the scenario in which you are fighting. Ball groups or large groups of enemies your typical rotation is:

Tab target middle of the group, Blastbones > Colossus > Boneyard > synergy.

This means you need to be near the group so have as much protection as you can. have your guardian up and any shields available as you will have to run into the ball to fire off the synergy.

During mobile fights use your force pulse, blastbones and boneyard as you can. Keep in mind that your boneyard activates your Dark Convergence so you will be using that synergy. This can be used for mini bombs or just to make sure they are in your graveyard for the synergy